Vaccines - Covid 19

[HHTel]

Your choice of course. However, the way things are going, you'll probably need a vaccination certificate to go for a pee outside of your home.
Vaccine certificates are increasingly required to do anything in many countries. Will it happen in Thailand? They may well mandate it, but we all know how well laws are enforced here!

[Big Boy]

I read yesterday that a vaccine certificate will be required to float your Krathong tonight in some places (not Hua Hin, I hasten to add). I think it's coming.

[GroveHillWanderer]

I agree that it doesn’t stop vaccinated people getting COVID, but I’m certain I’ve read somewhere that being vaccinated reduces (but doesn’t stop) the transmission, so the more people who get vaccinated, the less the transmission.

As BB has mentioned, we’re all still receiving the “first generation” of the vaccine (which was understandably rushed out in record breaking time to provide the best protection possible in the shortest possible time, hopefully the 2nd and 3rd generations will offer better protection.

From what I understand, the best (if not only) way to really cut down on transmission rate is to develop vaccines that stimulate mucosal immunity. The current vaccines don't really do that, so the virus can still gain a foothold in the mucosa of the nasal and throat areas. With the more transmissible variants like Delta, that allows the virus to spread before the systemic immunity generated by the current vaccines can take full effect.

So what we need are vaccines that are either inhaled or edible, since those are the methods of administration that best invoke mucosal immunity.

Various people are working on inhalable and edible vaccines but they're still some way away from completing phase 3 trials and/or being approved.

[handdrummer]

Your choice of course. However, the way things are going, you'll probably need a vaccination certificate to go for a pee outside of your home.
Vaccine certificates are increasingly required to do anything in many countries. Will it happen in Thailand? They may well mandate it, but we all know how well laws are enforced here!

If the fine is large enough to avoid it with a bribe, it will be enforced.

[HHTel]

From what I understand, the best (if not only) way to really cut down on transmission rate is to develop vaccines that stimulate mucosal immunity. The current vaccines don't really do that, so the virus can still gain a foothold in the mucosa of the nasal and throat areas. With the more transmissible variants like Delta, that allows the virus to spread before the systemic immunity generated by the current vaccines can take full effect.

So what we need are vaccines that are either inhaled or edible, since those are the methods of administration that best invoke mucosal immunity.

Various people are working on inhalable and edible vaccines but they're still some way away from completing phase 3 trials and/or being approved.

What you say makes sense. However, it's a very complex area and very difficult to study. Current studies are being done with animals. The animal has to be killed to investigate results. We're a long long way from any conclusions and even then it may be found fruitless.

In the meantime we're stuck with an RNA virus which will continue to mutate just like the 'flu and vaccines will have to develop for the mutations. It's been asked why polio vaccines and the like provide lifelong, or at least decades of protection but only limited protection for covid and other coronaviruses. It's the difference between an RNA virus and a DNA virus. The latter is a much simpler molecule and doesn't mutate or if it does it's so slow as to be insignificant.

Maybe one day, people will carry an inhaler that protects against all diseases. Not in my lifetime unfortunately.

[PeteC]

Vaccine side effects fund has paid out 621 million baht

https://thethaiger.com/coronavirus/vacc ... llion-baht

The program to pay financial compensation for anyone with mild or severe side effects after getting a Covid-19 vaccine has now paid out 621 million baht to 6,177 recipients. The National Health Security Office is responsible for the remedial assistance program that pays out up to 100,000 baht for mild side effects and up to 400,000 baht for side effects that lead to disability or death.

The NHSO programme to compensate negative effects of vaccination was created in an attempt to battle vaccine hesitance and instil confidence in people who feared getting a vaccine could harm them. Knowing they can get financial compensation if they get sick from a vaccine reassured many to get their inoculation.

Of the 9,245 people who have applied for compensation, 6,177 were confirmed eligible for financial assistance. Another 1,569 cases are still pending, awaiting a decision on if they are eligible for a payout or not. The eligible patients received a total of 621 million baht, which averages out to 100,534 baht per person.

The most applications for financial payouts in the vaccine program were from Bangkok so far. Chiang Mai, Ubon Ratchathani, and Udon Thani were the next most popular provinces for requesting compensation for vaccine side effects. 46% of the people who requested assistance were part of the gold-card universal health care system, while 27% were members of the social security programme. The remaining 27% were state officials.

A panel of experts and civic groups assess the applications received to determine eligibility. Anyone who has been affected negatively by vaccination can apply for compensation by visiting NHSO branches, provincial health offices, or wherever they received their shots. Claims must be submitted within 2 years of the side effects being discovered.

The NHSO said that 1,296 people were compensated up to 400,000 baht after vaccines left them disabled or dead, though they did not specify an individual figure for the number of deaths. 4,770 people were compensated up to 100,000 baht for mild side effects. The main side effects people suffered were nausea, breathing difficulties, fever, chest pain, weak legs and arms, and phylaxis shock.

SOURCE: Bangkok Post https://www.bangkokpost.com/thailand/ge ... -from-nhso

[Gregjam]

I finally get back to Thailand tomorrow after leaving for work at the end of April and have the joys of 11 days at an ASQ as it was not possible to get vaccinated at work. From what I gather at present all I need to do is walk in to the place in Bluport after noon to sort out the jab. If you want to book how do you do this? What proof of address do they want (will my Thai drivers licence suffice or the sheet attached into my passport at the immigration office (I am on a Non Imm O extension issued at Hua Hin Immigration).
My job requires me to be vaccinated and being over 60 (just) should help.
I will not get back to Hua Hin until 3rd December so still time to arrange something.

[HHTel]

side effects that lead to disability or death.

If I'm dead, I doubt whether I'll make a claim!

[GroveHillWanderer]

In the meantime we're stuck with an RNA virus which will continue to mutate just like the 'flu and vaccines will have to develop for the mutations. It's been asked why polio vaccines and the like provide lifelong, or at least decades of protection but only limited protection for covid and other coronaviruses. It's the difference between an RNA virus and a DNA virus. The latter is a much simpler molecule and doesn't mutate or if it does it's so slow as to be insignificant.

Maybe one day, people will carry an inhaler that protects against all diseases. Not in my lifetime unfortunately.

Coronaviruses (including this one) do mutate, but they don't mutate "just like the flu." In fact they mutate in a way that is quite fundamentally different to the influenza viruses, due to their different genetic characteristics.

Coronaviruses have unsegmented RNA, whereas the RNA of influenza viruses is made up of eight different genome segments.

Because of this, flu viruses are much more mutagenic as the segments can undergo a process called "reassortment" which leads to both antigenic drift and antigenic shift.

On the other hand, coronaviruses do not have segmented genomes and cannot reassort, so as mentioned in the article linked to below:

Unlike flu viruses, "Coronaviruses are not prone to undergo antigenic drift or shift."

https://www.astrazeneca.com/what-scienc ... ov-2.html

Antigenic drift is why you need brand new flu vaccines every single year, without fail and antigenic shift is why brand new strains of flu arise every so often, each of which again, requires a totally new vaccine to the previous strains. There are dozens of different varieties of the flu which if they were all prevalent each year, would require dozens of different vaccines to combat them. Luckily for us, there are usually only three or four strains that present a problem each year, so the flu vaccines that come out each year only contain antigens for the three or four most common strains that are in circulation at the time.

[HHTel]

Well I just gave the simplified version. If I knew this was a seminar rather than a forum I'd have gone into more detail and set an exam!!

[Dannie Boy]

Well it’s best to get the facts straight so thanks that we have the likes of GHW to make sure we stay on track!!


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[HHTel]

And are we any the wiser. 'flu can mutate in 6 hours. The new vaccine each year is based on an educated guess. Data collected around the world and decided upon by the WHO.
I very simply showed the difference between an RNA virus (constantly mutating) and a DNA virus which doesn't.

What else is relevant in a simple explanation that anyone can understand.

Anyway, I'll leave it. Too much information, as has often shown, is confusing to most.

[hhinner]

I finally get back to Thailand tomorrow after leaving for work at the end of April and have the joys of 11 days at an ASQ as it was not possible to get vaccinated at work. From what I gather at present all I need to do is walk in to the place in Bluport after noon to sort out the jab. If you want to book how do you do this? What proof of address do they want (will my Thai drivers licence suffice or the sheet attached into my passport at the immigration office (I am on a Non Imm O extension issued at Hua Hin Immigration).
My job requires me to be vaccinated and being over 60 (just) should help.
I will not get back to Hua Hin until 3rd December so still time to arrange something.

You can only do a walk-in if they are vaccinating at the time and have advertised walk-in is available.

You can register for vaccination here (English and Thai):
http://203.157.159.10/covid19.php

[hhinner]

I finally get back to Thailand tomorrow after leaving for work at the end of April and have the joys of 11 days at an ASQ as it was not possible to get vaccinated at work. From what I gather at present all I need to do is walk in to the place in Bluport after noon to sort out the jab. If you want to book how do you do this? What proof of address do they want (will my Thai drivers licence suffice or the sheet attached into my passport at the immigration office (I am on a Non Imm O extension issued at Hua Hin Immigration).
My job requires me to be vaccinated and being over 60 (just) should help.
I will not get back to Hua Hin until 3rd December so still time to arrange something.

You can only do a walk-in if they are vaccinating at the time and have advertised walk-in is available.

You can register for vaccination here (English and Thai):
http://203.157.159.10/covid19.php

Just to make it easier (hopefully) here's the actual form.
https://docs.google.com/forms/d/e/1FAIp ... A/viewform

[Gregjam]

Thanks hhinner for the link. I will wait until I am in the ASQ hotel later today before submitting anything. Don’t want to tempt fate before I get back in.